Gemigliptin tartrate is the tartrate salt form of gemigliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor used for the treatment of type 2 diabetes mellitus. It improves glycemic control by inhibiting DPP-4, thereby increasing the levels of incretin hormones (GLP-1 and GIP), which enhance insulin secretion and suppress glucagon release in a glucose-dependent manner. Gemigliptin tartrate is orally administered and typically used as monotherapy or in combination with other antidiabetic agents.
MedKoo Cat#: 471178
Name: Gemigliptin tartrate
CAS#: 1374639-74-3 (tartrate)
Chemical Formula: C22H25F8N5O8
Exact Mass: 0.0000
Molecular Weight: 639.46
Elemental Analysis: C, 41.32; H, 3.94; F, 23.77; N, 10.95; O, 20.02
The following data is based on the product molecular weight 639.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
