Phenyl-glutarimide 4'-oxyacetic acid is a carboxylic acid-functionalized cereblon ligand that can be used for PROTAC® Degrader development. The compound exhibits improved stability to hydrolysis compared with IMiD (immunomodulatory imide drug) analogs.
MedKoo Cat#: 466266
Name: Phenyl-glutarimide 4'-oxyacetic acid
CAS#: unknown
Chemical Formula: C13H13NO5
Exact Mass: 263.0794
Molecular Weight: 263.25
Elemental Analysis: C, 59.31; H, 4.98; N, 5.32; O, 30.39
The following data is based on the product molecular weight 263.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
