MedKoo Cat#: 208114 | Name: CDK1-IN-2
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CDK1-IN-2, also known as CDK1 inhibitor 8a, is a selective CDK1 inhibitor. This compound was first reported by Andreani, Aldo; et al in Anti-Cancer Drug Design (2001), 15(6), 447-452. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

CDK1-IN-2
CDK1-IN-2
CAS#220749-41-7

Theoretical Analysis

MedKoo Cat#: 208114

Name: CDK1-IN-2

CAS#: 220749-41-7

Chemical Formula: C17H11ClN2O

Exact Mass: 294.0560

Molecular Weight: 294.74

Elemental Analysis: C, 69.28; H, 3.76; Cl, 12.03; N, 9.50; O, 5.43

Price and Availability

Size Price Availability Quantity
100mg USD 1,250.00 2 Weeks
200mg USD 1,950.00 2 Weeks
500mg USD 2,950.00 2 Weeks
1g USD 4,650.00 2 Weeks
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Related CAS #
No Data
Synonym
CDK1 inhibitor 8a; CDK1inhibitor8a; CDK1-inhibitor-8a, Cdk1 Inhibitor; CDK1-IN-2; CDK1 IN-2; CDK1-IN 2
IUPAC/Chemical Name
(Z)-3-((2-chloro-1H-indol-3-yl)methylene)indolin-2-one
InChi Key
QJKBRWSJWQVKLY-LCYFTJDESA-N
InChi Code
InChI=1S/C17H11ClN2O/c18-16-12(10-5-1-3-7-14(10)19-16)9-13-11-6-2-4-8-15(11)20-17(13)21/h1-9,19H,(H,20,21)/b13-9-
SMILES Code
ClC(N1)=C(/C=C2C(C=CC=C3)=C3NC/2=O)C4=C1C=CC=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 294.74 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Jorda R, Hendrychová D, Voller J, Řezníčková E, Gucký T, Kryštof V. How Selective Are Pharmacological Inhibitors of Cell-Cycle-Regulating Cyclin-Dependent Kinases? J Med Chem. 2018 Oct 25;61(20):9105-9120. doi: 10.1021/acs.jmedchem.8b00049. Epub 2018 Oct 5. PMID: 30234987.