Levamisole hydrochloride is the orally bioavailable hydrochloride salt of the synthetic imidazothiazole derivative levamisole with anthelminthic and immunostimulating activities. In immunosuppressed states, levamisole may restore immune function by: 1) stimulating antibody formation, 2) stimulating T-cell activation and proliferation, 3) potentiatiating monocyte and macrophage phagocytosis and chemotaxis and 4) increasing neutrophil mobility, adherence, and chemotaxis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
MedKoo Cat#: 100540
Name: Levamisole hydrochloride
CAS#: 16595-80-5 (HCl)
Chemical Formula: C11H12N2S
Exact Mass: 240.0488
Molecular Weight: 240.75
Elemental Analysis: C, 64.67; H, 5.92; N, 13.71; S, 15.70
Solvent | mg/mL | mM | comments | |
---|---|---|---|---|
Solubility | ||||
DMSO | 13.8 | 57.11 | ||
Ethanol | 30.3 | 125.65 | ||
Water | 49.0 | 203.53 |
The following data is based on the product molecular weight 240.75 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
50 mM | 0.02 mL | 0.12 mL | 0.23 mL |