MedKoo Cat#: 556091 | Name: (R)-AM-5308
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

(R)-AM-5308 is a potent kinesin KIF18A inhibitor

Chemical Structure

(R)-AM-5308
(R)-AM-5308
CAS#2410796-89-1

Theoretical Analysis

MedKoo Cat#: 556091

Name: (R)-AM-5308

CAS#: 2410796-89-1

Chemical Formula: C26H35N5O5S

Exact Mass: 529.2359

Molecular Weight: 529.66

Elemental Analysis: C, 58.96; H, 6.66; N, 13.22; O, 15.10; S, 6.05

Price and Availability

Size Price Availability Quantity
5mg USD 750.00 2 Weeks
10mg USD 1,250.00 2 Weeks
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Related CAS #
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Synonym
(R)-AM-5308; (R)-AM 5308; (R)-AM5308;
IUPAC/Chemical Name
Benzamide, 2-(6-azaspiro[2.5]oct-6-yl)-4-[[(2-hydroxyethyl)sulfonyl]amino]-N-[6-[(2R)-2-methyl-4-morpholinyl]-2-pyridinyl]-
InChi Key
IUDCFCQNVQWCCI-LJQANCHMSA-N
InChi Code
InChI=1S/C26H35N5O5S/c1-19-18-31(13-15-36-19)24-4-2-3-23(27-24)28-25(33)21-6-5-20(29-37(34,35)16-14-32)17-22(21)30-11-9-26(7-8-26)10-12-30/h2-6,17,19,29,32H,7-16,18H2,1H3,(H,27,28,33)/t19-/m1/s1
SMILES Code
O=C(NC1=NC(N2C[C@@H](C)OCC2)=CC=C1)C3=CC=C(NS(=O)(CCO)=O)C=C3N(CC4)CCC54CC5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 529.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
[1]. Marc Noel PAYTON, et al. Kif18a inhibitors for treatment of neoplastic diseases. WO2021211549A1. https://patents.google.com/patent/WO2021211549A1