NRC-2694 HCl | CAS# 1172626-99-1 | Biochemical

MedKoo Cat#: 578333 | Name: NRC-2694 hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NRC-2694 hydrochloride is an epidermal growth factor receptor (EGFR) antagonist potentially for the treatment of solid tumors.

Chemical Structure

NRC-2694 hydrochloride

CAS#1172626-99-1

Theoretical Analysis

MedKoo Cat#: 578333

Name: NRC-2694 hydrochloride

CAS#: 1172626-99-1

Chemical Formula: C24H27ClN4O3

Exact Mass: 454.1772

Molecular Weight: 454.95

Elemental Analysis: C, 63.36; H, 5.98; Cl, 7.79; N, 12.32; O, 10.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NRC-2694 hydrochloride; NRC 2694 hydrochloride; NRC2694 hydrochloride; NRC-2694 HCl; NRC 2694 HCl; NRC2694 HCl

IUPAC/Chemical Name

N-(3-Ethynylphenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine monohydrochloride

InChi Key

YHFOWANFLQFAKF-UHFFFAOYSA-N

InChi Code

1S/C24H26N4O3.ClH/c1-3-18-6-4-7-19(14-18)27-24-20-15-23(22(29-2)16-21(20)25-17-26-24)31-11-5-8-28-9-12-30-13-10-28;/h1,4,6-7,14-17H,5,8-13H2,2H3,(H,25,26,27);1H

SMILES Code

Cl.COc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCCN4CCOCC4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 454.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Wagner EF, Nebreda AR. Signal integration by JNK and p38 MAPK pathways in cancer development. Nat Rev Cancer. 2009 Aug;9(8):537-49. doi: 10.1038/nrc2694. Review. PubMed PMID: 19629069.