JAR1.39 | CAS# | JAR1.39

MedKoo Cat#: 208074 | Name: JAR1.39

Description:

WARNING: This product is for research use only, not for human or veterinary use.

JAR1.39 is a mitophagy inducer that induces Parkin-dependent mitophagy.

Chemical Structure

JAR1.39

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 208074

Name: JAR1.39

CAS#: N/A

Chemical Formula: C24H34BrN3O4

Exact Mass: 507.1733

Molecular Weight: 508.46

Elemental Analysis: C, 56.69; H, 6.74; Br, 15.71; N, 8.26; O, 12.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

JAR1.39; JAR-1.39; JAR 1.39

IUPAC/Chemical Name

6-bromo-N'-dodecanoyl-1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbohydrazide

InChi Key

DLFISVVCJZZGCR-UHFFFAOYSA-N

InChi Code

InChI=1S/C24H34BrN3O4/c1-3-5-6-7-8-9-10-11-12-13-20(29)26-27-23(31)21-22(30)18-16-17(25)14-15-19(18)28(4-2)24(21)32/h14-16,30H,3-13H2,1-2H3,(H,26,29)(H,27,31)

SMILES Code

BrC1=CC(C(O)=C(C(NNC(CCCCCCCCCCC)=O)=O)C(N2CC)=O)=C2C=C1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 508.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Maestro I, de la Ballina LR, Simonsen A, Boya P, Martinez A. Phenotypic Assay Leads to Discovery of Mitophagy Inducers with Therapeutic Potential for Parkinson's Disease. ACS Chem Neurosci. 2021 Dec 15;12(24):4512-4523. doi: 10.1021/acschemneuro.1c00529. Epub 2021 Nov 30. PMID: 34846852.