NNZ-2591 | CAS# 847952-38-9 | Biochemical

MedKoo Cat#: 578260 | Name: NNZ-2591

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NNZ-2591 is a modified diketopiperazine neuroprotectant that improves long-term function after hypoxic-ischaemic brain injury in rats.

Chemical Structure

NNZ-2591

CAS#847952-38-9

Theoretical Analysis

MedKoo Cat#: 578260

Name: NNZ-2591

CAS#: 847952-38-9

Chemical Formula: C10H14N2O2

Exact Mass: 194.1055

Molecular Weight: 194.23

Elemental Analysis: C, 61.84; H, 7.27; N, 14.42; O, 16.47

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

NNZ-2591; NNZ 2591; NNZ2591

IUPAC/Chemical Name

Pyrrolo(1,2-a)pyrazine-1,4-dione, hexahydro-8a-(2-propenyl)-, (8aR)-

InChi Key

WVKCGUOWPZAROG-JTQLQIEISA-N

InChi Code

InChI=1S/C10H14N2O2/c1-2-4-10-5-3-6-12(10)8(13)7-11-9(10)14/h2H,1,3-7H2,(H,11,14)/t10-/m0/s1

SMILES Code

C=CC[C@@]12CCCN1C(=O)CNC2=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 194.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Guan J, Zhang R, Dale-Gandar L, Hodgkinson S, Vickers MH. NNZ-2591, a novel diketopiperazine, prevented scopolamine-induced acute memory impairment in the adult rat. Behav Brain Res. 2010 Jul 11;210(2):221-8. doi: 10.1016/j.bbr.2010.02.039. Epub 2010 Feb 25. PMID: 20188767. 2. Guan J, Mathai S, Harris P, Wen JY, Zhang R, Brimble M, Gluckman P. Peripheral administration of a novel diketopiperazine, NNZ 2591, prevents brain injury and improves somatosensory-motor function following hypoxia-ischemia in adult rats. Neuropharmacology. 2007 Nov;53(6):749-62. doi: 10.1016/j.neuropharm.2007.08.010. Epub 2007 Aug 19. PMID: 17904590.