QPX7831 Sodium | CAS# unknown | Novel orally bioavailable prodrug

MedKoo Cat#: 208008 | Name: QPX7831 Sodium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Novel Orally Bioavailable Prodrug of Boronic Acid β-Lactamase Inhibitor QPX7728 (GLXC-22429)

Chemical Structure

QPX7831 Sodium

CAS#N/A

Theoretical Analysis

MedKoo Cat#: 208008

Name: QPX7831 Sodium

CAS#: N/A

Chemical Formula: C15H15BFNaO6

Exact Mass: 344.0843

Molecular Weight: 344.08

Elemental Analysis: C, 52.36; H, 4.39; B, 3.14; F, 5.52; Na, 6.68; O, 27.90

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

QPX7831 Sodium; QPX7831Sodium

IUPAC/Chemical Name

Sodium (1aR,7bS)-5-fluoro-4-(((isobutyryloxy)methoxy)carbonyl)-1a,7b-dihydrobenzo[e]cyclopropa[c][1,2]oxaborinin-2(1H)-olate

InChi Key

YFLAXRHSCNOJBN-DHTOPLTISA-N

InChi Code

InChI=1S/C15H15BFO6.Na/c1-7(2)14(18)21-6-22-15(19)12-11(17)4-3-8-9-5-10(9)16(20)23-13(8)12;/h3-4,7,9-10H,5-6H2,1-2H3;/q-1;+1/t9-,10-;/m1./s1

SMILES Code

CC(C)C(OCOC(C1=C(OB(O[Na])[C@@H]2C[C@@H]23)C3=CC=C1F)=O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 344.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Reddy KR, Parkinson J, Sabet M, Tarazi Z, Boyer SH, Lomovskaya O, Griffith DC, Hecker SJ, Dudley MN. Selection of QPX7831, an Orally Bioavailable Prodrug of Boronic Acid β-Lactamase Inhibitor QPX7728. J Med Chem. 2021 Dec 9;64(23):17523-17529. doi: 10.1021/acs.jmedchem.1c01722. Epub 2021 Nov 24. PMID: 34817182.