LDC0496 is a potent EGFR inhibitor. LDC0496 exhibited intense inhibitory potency toward EGFR and Her2 exon20 insertion mutations as well as selectivity over wild type EGFR and within the kinome.
MedKoo Cat#: 466213
Name: LDC0496
CAS#: unknown
Chemical Formula: C32H35N5O3
Exact Mass: 537.2740
Molecular Weight: 537.66
Elemental Analysis: C, 71.49; H, 6.56; N, 13.03; O, 8.93
The following data is based on the product molecular weight 537.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
