NCX-8001 | CAS# 679837-89-9 | Biochemical

MedKoo Cat#: 578019 | Name: NCX-8001

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NCX-8001 is a nitric oxide (NO)-releasing derivative of gabapentin.

Chemical Structure

NCX-8001

CAS#679837-89-9

Theoretical Analysis

MedKoo Cat#: 578019

Name: NCX-8001

CAS#: 679837-89-9

Chemical Formula: C16H22N2O4

Exact Mass: 306.1580

Molecular Weight: 306.36

Elemental Analysis: C, 62.73; H, 7.24; N, 9.14; O, 20.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NCX-8001; NCX 8001; NCX8001

IUPAC/Chemical Name

3-(nitromethyl)phenyl 2-(1-(aminomethyl)cyclohexyl)acetate

InChi Key

BKKQAFYHGAYCCS-UHFFFAOYSA-N

InChi Code

1S/C16H22N2O4/c17-12-16(7-2-1-3-8-16)10-15(19)22-14-6-4-5-13(9-14)11-18(20)21/h4-6,9H,1-3,7-8,10-12,17H2

SMILES Code

NCC1(CC(=O)Oc2cccc(C[N+](=O)[O-])c2)CCCCC1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 306.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Wu WP, Hao JX, Ongini E, Impagnatiello F, Presotto C, Wiesenfeld-Hallin Z, Xu XJ. A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury. Br J Pharmacol. 2004 Jan;141(1):65-74. doi: 10.1038/sj.bjp.0705596. Epub 2003 Dec 8. PMID: 14662726; PMCID: PMC1574179.