F-1322 | CAS# 143964-80-1 | Biochemical

MedKoo Cat#: 578009 | Name: F-1322

Description:

WARNING: This product is for research use only, not for human or veterinary use.

F-1322 is an anti-asthmatic agent.

Chemical Structure

F-1322

CAS#143964-80-1

Theoretical Analysis

MedKoo Cat#: 578009

Name: F-1322

CAS#: 143964-80-1

Chemical Formula: C37H37N3O4

Exact Mass: 587.2784

Molecular Weight: 587.72

Elemental Analysis: C, 75.62; H, 6.35; N, 7.15; O, 10.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

F-1322; F 1322; F1322; NC-2000; NC 2000; NC2000; SOA 132; SOA-132; SOA132

IUPAC/Chemical Name

N-(2-(4-(Diphenylmethoxy)-1-piperidinyl)ethyl)-3-hydroxy-5-(3-pyridinylmethoxy)-2-naphthalenecarboxamide

InChi Key

ZBOYHAZRFJBUEL-UHFFFAOYSA-N

InChi Code

1S/C37H37N3O4/c41-34-24-32-30(14-7-15-35(32)43-26-27-9-8-18-38-25-27)23-33(34)37(42)39-19-22-40-20-16-31(17-21-40)44-36(28-10-3-1-4-11-28)29-12-5-2-6-13-29/h1-15,18,23-25,31,36,41H,16-17,19-22,26H2,(H,39,42)

SMILES Code

Oc1cc2c(OCc3cccnc3)cccc2cc1C(=O)NCCN4CCC(CC4)OC(c5ccccc5)c6ccccc6

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 587.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Mochizuki A, Tamura N, Yatabe Y, Onodera S, Hiruma T, Inaba N, Kusunoki J, Tomioka H. Suppressive effects of F-1322 on the antigen-induced late asthmatic response and pulmonary eosinophilia in guinea pigs. Eur J Pharmacol. 2001 Oct 26;430(1):123-33. doi: 10.1016/s0014-2999(01)01364-4. PMID: 11698072. 2. Lee B, Takasaki K, Mochizuki A, Tamura N, Higashide Y, Yamaura T. [Pharmacological profiles of F-1322, a novel anti-asthmatic agent. (1). Mechanisms of action]. Nihon Yakurigaku Zasshi. 1995 Jul;106(1):31-40. Japanese. doi: 10.1254/fpj.106.31. PMID: 7590521. 3. Mochizuki A, Lee B, Shibata M, Kasai M, Tanaka T, Iwamoto I. Inhibitory effect of F-1322 on allergic eosinophil infiltration in airways. Eur J Pharmacol. 1998 Feb 19;343(2-3):233-7. doi: 10.1016/s0014-2999(97)01534-3. PMID: 9570472.