Naroparcil | CAS# 120819-70-7 | Biochemical

MedKoo Cat#: 577977 | Name: Naroparcil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Naroparcil is an antithrombotic agent.

Chemical Structure

Naroparcil

CAS#120819-70-7

Theoretical Analysis

MedKoo Cat#: 577977

Name: Naroparcil

CAS#: 120819-70-7

Chemical Formula: C19H17NO4S2

Exact Mass: 387.0599

Molecular Weight: 387.47

Elemental Analysis: C, 58.90; H, 4.42; N, 3.62; O, 16.52; S, 16.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Naroparcil

IUPAC/Chemical Name

p-(p-((5-Thio-beta-D-xylopyranosyl)thio)benzoyl)benzonitrile

InChi Key

IMAFEPKOGMHYNH-LULLPPNCSA-N

InChi Code

InChI=1S/C19H17NO4S2/c20-9-11-1-3-12(4-2-11)16(22)13-5-7-14(8-6-13)26-19-18(24)17(23)15(21)10-25-19/h1-8,15,17-19,21,23-24H,10H2/t15-,17+,18-,19+/m1/s1

SMILES Code

O[C@@H]1CS[C@@H](Sc2ccc(cc2)C(=O)c3ccc(cc3)C#N)[C@H](O)[C@H]1O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 387.47 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Masson PJ, Coup D, Millet J, Brown NL. The effect of the beta-D-xyloside naroparcil on circulating plasma glycosaminoglycans. An explanation for its known antithrombotic activity in the rabbit. J Biol Chem. 1995 Feb 10;270(6):2662-8. doi: 10.1074/jbc.270.6.2662. PMID: 7852334. 2. Steg PG, Ziol M, Tahlil O, Robert C, Masson P, Pruneau D, Bruneval P, Bélichard P. Reduction of intimal hyperplasia by naroparcil, a 4-methylumbelliferyl beta-D-xyloside analogue, after arterial injury in the hypercholesterolemic rabbit. Circ Res. 1995 Nov;77(5):919-26. doi: 10.1161/01.res.77.5.919. PMID: 7554145. 3 .Millet J, Theveniaux J, Brown NL. The venous antithrombotic profile of naroparcil in the rabbit. Thromb Haemost. 1994 Dec;72(6):874-9. PMID: 7740457. 4. Masson P, Theveniaux J, Coup D, Grégoire T, Vaillot M, Dupouy D, Sié P, Boneu B, Millet J. Further studies on the mechanism for the antithrombotic effects of naroparcil, an orally active thiozyloside compound. Thromb Haemost. 1999 Jun;81(6):945-50. PMID: 10404773.