Berdoxam, a hypoxia-activated prodrug, exhibits bioactivity primarily through its selective activation under low-oxygen conditions, leading to the release of cytotoxic metabolites that target hypoxic tumor cells. Bioactivity data for Berdoxam are crucial for evaluating its pharmacokinetics, metabolic activation, and anticancer efficacy in preclinical and clinical studies. These data inform dose-response relationships, mechanism of action studies, and potential combination therapies. Additionally, bioactivity profiling helps in assessing off-target effects, resistance mechanisms, and optimizing drug formulations for improved therapeutic outcomes.
MedKoo Cat#: 577922
Name: Berdoxam
CAS#: 1222468-90-7
Chemical Formula: C33H52N8O8S2
Exact Mass: 752.3350
Molecular Weight: 752.95
Elemental Analysis: C, 52.64; H, 6.96; N, 14.88; O, 17.00; S, 8.52
The following data is based on the product molecular weight 752.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
