Synonym
Bay-85-8050; Bay85-8050; Bay 85-8050; Bay-858050; Bay-85 8050; Bay858050; Bay 85 8050;
IUPAC/Chemical Name
4-(Fluoro-18F)-L-glutamic acid
InChi Key
JPSHPWJJSVEEAX-OWPBQMJCSA-N
InChi Code
InChI=1S/C5H8FNO4/c6-2(4(8)9)1-3(7)5(10)11/h2-3H,1,7H2,(H,8,9)(H,10,11)/t2?,3-/m0/s1/i6-1
SMILES Code
N[C@@H](CC([18F])C(O)=O)C(O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
164.12
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Smolarz K, Krause BJ, Graner FP, Wagner FM, Wester HJ, Sell T, Bacher-Stier C, Fels L, Dinkelborg L, Schwaiger M. Biodistribution and radiation dosimetry in healthy volunteers of a novel tumour-specific probe for PET/CT imaging: BAY 85-8050. Eur J Nucl Med Mol Imaging. 2013 Dec;40(12):1861-8. doi: 10.1007/s00259-013-2502-z. Epub 2013 Jul 23. PMID: 23877631.
2: Krasikova RN, Kuznetsova OF, Fedorova OS, Belokon YN, Maleev VI, Mu L, Ametamey S, Schubiger PA, Friebe M, Berndt M, Koglin N, Mueller A, Graham K, Lehmann L, Dinkelborg LM. 4-[18F]fluoroglutamic acid (BAY 85-8050), a new amino acid radiotracer for PET imaging of tumors: synthesis and in vitro characterization. J Med Chem. 2011 Jan 13;54(1):406-10. doi: 10.1021/jm101068q. Epub 2010 Dec 3. PMID: 21128591.
