MedKoo Cat#: 466053 | Name: Antimonyl potassium tartrate trihydrate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Potassium antimonyl tartrate trihydrate is a metalloid salt in which the antimony is in trivalent state (SbIII). Potassium antimonyl tartrate (PAT) is an antiparasitic agent predominantly used for treating infections caused by the parasite Leishmania. Its antiangiogenic and antitumor properties has been investigated in nonsmall-cell lung cancer (NSCLC) cells. Studies in Chinese hamster ovary cells show that it may prevent the repair of DNA double strand breaks (DSBs) caused by γ-irradiation.

Chemical Structure

Antimonyl potassium tartrate trihydrate
Antimonyl potassium tartrate trihydrate
CAS#28300-74-5 (potassium hydrate)

Theoretical Analysis

MedKoo Cat#: 466053

Name: Antimonyl potassium tartrate trihydrate

CAS#: 28300-74-5 (potassium hydrate)

Chemical Formula: C8H10K2O15Sb2

Exact Mass: 665.7370

Molecular Weight: 667.87

Elemental Analysis: C, 14.39; H, 1.51; K, 11.71; O, 35.93; Sb, 36.46

Price and Availability

Size Price Availability Quantity
5g USD 350.00 2 Weeks
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Synonym
Antimonyl potassium tartrate trihydrate; Tartar emetic; Potassium antimonyl tartrate trihydrate; PAT;
IUPAC/Chemical Name
N/A
InChi Key
WBTCZEPSIIFINA-UHFFFAOYSA-J
InChi Code
InChI=1S/2C4H4O6.2K.3H2O.2Sb/c2*5-1(3(7)8)2(6)4(9)10;;;;;;;/h2*1-2H,(H,7,8)(H,9,10);;;3*1H2;;/q2*-2;2*+1;;;;2*+3/p-4
SMILES Code
O=C1C(C2O[Sb-]34OC2=O)O[Sb-]5(OC(C(C(C(O4)=O)O3)O5)=O)O1.O.O.O.[K+].[K+]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 667.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sereno D, Lemesre JL. Axenically cultured amastigote forms as an in vitro model for investigation of antileishmanial agents. Antimicrob Agents Chemother. 1997 May;41(5):972-6. doi: 10.1128/AAC.41.5.972. PMID: 9145854; PMCID: PMC163835. 2: Dieter M. NTP technical report on the toxicity studies of Toxicity Studies of Antimony Potassium Tartrate (CAS No. 28300-74-5) in F344/N Rats And B6C3F1 Mice (Drinking Water and Intraperitoneal Injection Studies). Toxic Rep Ser. 1992 Mar;11:1-D2. PMID: 12209175.