Eluxadoline dihydrochloride is an orally-active drug approved for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D). Eluxadoline is a μ- and κ-opioid receptor agonist and δ-opioid receptor antagonist that acts locally in the enteric nervous system, possibly decreasing adverse effects on the central nervous system. This product is discontinued (DEA Schedule IV).
MedKoo Cat#: 577808
Name: Eluxadoline dihydrochloride
CAS#: 864825-13-8
Chemical Formula: C32H37Cl2N5O5
Exact Mass: 641.2172
Molecular Weight: 642.58
Elemental Analysis: C, 59.81; H, 5.80; Cl, 11.03; N, 10.90; O, 12.45
The following data is based on the product molecular weight 642.58 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
