MS-377 dihydroxybutanedioate | CAS# 206862-48-8 | Biochemical

MedKoo Cat#: 577792 | Name: MS-377 dihydroxybutanedioate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MS-377 dihydroxybutanedioate is a novel antipsychotic agent with selective affinity for sigma receptors.

Chemical Structure

MS-377 dihydroxybutanedioate

CAS#206862-48-8

Theoretical Analysis

MedKoo Cat#: 577792

Name: MS-377 dihydroxybutanedioate

CAS#: 206862-48-8

Chemical Formula: C22H32ClN3O8

Exact Mass: 501.1878

Molecular Weight: 501.96

Elemental Analysis: C, 52.64; H, 6.43; Cl, 7.06; N, 8.37; O, 25.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

MS-377 dihydroxybutanedioate; MS 377 dihydroxybutanedioate; MS377 dihydroxybutanedioate

IUPAC/Chemical Name

2-Pyrrolidinone, 1-(4-chlorophenyl)-3-((4-(2-methoxyethyl)-1-piperazinyl)methyl)-, (R)-, (R-(R*,R*))-2,3-dihydroxybutanedioate (1:1)

InChi Key

CZURVZMARWUXMH-KBYGAXRISA-N

InChi Code

1S/C18H26ClN3O2.C4H6O6/c1-24-13-12-20-8-10-21(11-9-20)14-15-6-7-22(18(15)23)17-4-2-16(19)3-5-17;5-1(3(7)8)2(6)4(9)10/h2-5,15H,6-14H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t15-;1-,2-/m11/s1

SMILES Code

COCCN1CCN(C[C@H]2CCN(C2=O)c3ccc(Cl)cc3)CC1.O[C@H]([C@@H](O)C(=O)O)C(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 501.96 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Takahashi S, Sonehara K, Takagi K, Miwa T, Horikomi K, Mita N, Nagase H, Iizuka K, Sakai K. Pharmacological profile of MS-377, a novel antipsychotic agent with selective affinity for sigma receptors. Psychopharmacology (Berl). 1999 Aug;145(3):295-302. doi: 10.1007/s002130051061. PMID: 10494578.