Verubulin hydrochloride is a quinazoline derivative with potential dual antineoplastic activities. Verubulin binds to and inhibits tubulin polymerization and interrupts microtubule formation, resulting in disruption of mitotic spindle assembly, cell cycle arrest in the G2/M phase, and cell death.
MedKoo Cat#: 577772
Name: Verubulin hydrochloride
CAS#: 917369-31-4
Chemical Formula: C17H18ClN3O
Exact Mass: 315.1138
Molecular Weight: 315.80
Elemental Analysis: C, 64.66; H, 5.75; Cl, 11.23; N, 13.31; O, 5.07
The following data is based on the product molecular weight 315.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
