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MedKoo Cat#: 465899 | Name: MMV688844

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MMV688844 is a piperidine-4-carboxamide (P4C) with bactericidal properties against M. abscessus.

Chemical Structure

MMV688844
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465899

Name: MMV688844

CAS#: unknown

Chemical Formula: C23H25ClN4O2

Exact Mass: 424.1666

Molecular Weight: 424.93

Elemental Analysis: C, 65.01; H, 5.93; Cl, 8.34; N, 13.19; O, 7.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MMV688844; MMV 688844; MMV-688844;
IUPAC/Chemical Name
1-(4-chlorophenethyl)-N-(6-methoxy-1,5-naphthyridin-4-yl)piperidine-4-carboxamide
InChi Key
LBEJUQWGEGOTNX-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H25ClN4O2/c1-30-21-7-6-19-22(27-21)20(8-12-25-19)26-23(29)17-10-14-28(15-11-17)13-9-16-2-4-18(24)5-3-16/h2-8,12,17H,9-11,13-15H2,1H3,(H,25,26,29)
SMILES Code
COC1=CC=C(N=CC=C2NC(C3CCN(CCC4=CC=C(Cl)C=C4)CC3)=O)C2=N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 424.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Negatu DA, Beuchel A, Madani A, Alvarez N, Chen C, Aragaw WW, Zimmerman MD, Laleu B, Gengenbacher M, Dartois V, Imming P, Dick T. Piperidine-4-Carboxamides Target DNA Gyrase in Mycobacterium abscessus. Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0067621. doi: 10.1128/AAC.00676-21. Epub 2021 Jul 16. PMID: 34001512; PMCID: PMC8284461. 2: Jeong J, Kim G, Moon C, Kim HJ, Kim TH, Jang J. Pathogen Box screening for hit identification against Mycobacterium abscessus. PLoS One. 2018 Apr 26;13(4):e0195595. doi: 10.1371/journal.pone.0195595. PMID: 29698397; PMCID: PMC5919404.