SHR5133 is a Highly Potent and Novel HBV Capsid Assembly Modulator (HBV DNA EC50=26 nM). SHR5133 showed high in vitro antiviral potency, favorable pharmacokinetic profiles across species, and robust in vivo efficacy.
MedKoo Cat#: 465832
Name: SHR5133
CAS#: 2270943-23-0
Chemical Formula: C19H18F4N6O2
Exact Mass: 438.1427
Molecular Weight: 438.39
Elemental Analysis: C, 52.06; H, 4.14; F, 17.33; N, 19.17; O, 7.30
The following data is based on the product molecular weight 438.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
