Kirrothricin | CAS# 79190-00-4 | Biochemical

MedKoo Cat#: 577563 | Name: Kirrothricin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Kirrothricin is an antibiotic produced by Streptomyces cinnamoneus.

Chemical Structure

Kirrothricin

CAS#79190-00-4

Theoretical Analysis

MedKoo Cat#: 577563

Name: Kirrothricin

CAS#: 79190-00-4

Chemical Formula: C44H64N2O10

Exact Mass: 780.4561

Molecular Weight: 781.00

Elemental Analysis: C, 67.67; H, 8.26; N, 3.59; O, 20.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Kirrothricin

IUPAC/Chemical Name

N-((2E,4E,10E,12E,14E,16E)-8,9-dihydroxy-18-(4-hydroxy-1-methyl-2-oxo-1,2,5,6-tetrahydropyridin-3-yl)-6-methoxy-5,7,17-trimethyl-18-oxooctadeca-2,4,10,12,14,16-hexaen-1-yl)-2-((2S,4S,6S)-2,4-dihydroxy-5,5-dimethyl-6-((1E,3Z)-penta-1,3-dien-1-yl)tetrahydro-2H-pyran-2-yl)butanamide

InChi Key

GFPYWBPGDHFJDP-PWXLXMISSA-N

InChi Code

InChI=1S/C44H64N2O10/c1-10-12-16-24-36-43(6,7)35(49)28-44(54,56-36)32(11-2)41(52)45-26-20-19-22-30(4)40(55-9)31(5)39(51)34(48)23-18-15-13-14-17-21-29(3)38(50)37-33(47)25-27-46(8)42(37)53/h10,12-24,31-32,34-36,39-40,47-49,51,54H,11,25-28H2,1-9H3,(H,45,52)/b12-10-,15-13+,17-14+,20-19+,23-18+,24-16+,29-21+,30-22+/t31?,32?,34?,35-,36-,39?,40?,44-/m0/s1

SMILES Code

CCC(C(=O)NC\C=C\C=C(/C)\C(OC)C(C)C(O)C(O)\C=C\C=C\C=C\C=C(/C)\C(=O)C1=C(O)CCN(C)C1=O)[C@]2(O)C[C@H](O)C(C)(C)[C@@H](O2)\C=C\C=C/C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 781.00 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Thein-Schranner I, Zähner H, Hoppe HU, Hummel I, Zeeck A. Metabolic products of microorganisms. 209 Kirrothricin, a new member of the kirromycin-group. J Antibiot (Tokyo). 1982 Aug;35(8):948-56. doi: 10.7164/antibiotics.35.948. PMID: 7142013. 2. Cappellano C, Monti F, Sosio M, Donadio S, Sarubbi E. Natural kirromycin resistance of elongation factor Tu from the kirrothricin producer Streptomyces cinnamoneus. Microbiology (Reading). 1997 Feb;143 ( Pt 2):617-624. doi: 10.1099/00221287-143-2-617. PMID: 9043138.