MedKoo Cat#: 471093 | Name: ILS-920

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ILS-920 is a nonimmunosuppressive Rapamycin analog with reduced immunosuppressive activity and potent neuroprotective activity. ILS-920 binds selectively to the immunophilin FKBP52.

Chemical Structure

ILS-920
ILS-920
CAS#892494-07-4

Theoretical Analysis

MedKoo Cat#: 471093

Name: ILS-920

CAS#: 892494-07-4

Chemical Formula: C57H86N2O14

Exact Mass: 1022.6100

Molecular Weight: 1023.31

Elemental Analysis: C, 66.90; H, 8.47; N, 2.74; O, 21.89

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ILS-920; ILS920; ILS 920; WAY-265920; WAY265920; WAY 265920
IUPAC/Chemical Name
23,27-Epoxy-15,18-ethenopyrido(2,1-R)(1,16,2,19)dioxadiazacyclohentriacontine-1,5,11,28,29(6H,12H,31H)-pentone, 3,4,9,10,13,14,15,16,18,21,22,23,24,25,26,27,32,33,34,34a-eicosahydro-9,27-dihydroxy-3-((1R)-2-((1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl)-
InChi Key
WZFNBQBUDJACCD-ZSYWEHCUSA-N
InChi Code
InChI=1S/C57H86N2O14/c1-33-26-37(5)51(62)53(70-10)52(63)38(6)27-34(2)47(61)32-49(35(3)28-40-20-24-46(60)50(30-40)69-9)71-56(66)45-18-14-15-25-58(45)55(65)54(64)57(67)39(7)19-21-42(72-57)31-48(68-8)36(4)29-43-22-23-44(33)59(73-43)41-16-12-11-13-17-41/h11-13,16-17,27,29,33-35,37,39-40,42-46,48-50,52-53,60,63,67H,14-15,18-26,28,30-32H2,1-10H3/b36-29+,38-27+/t33-,34+,35+,37+,39+,40-,42-,43+,44-,45-,46+,48-,49-,50+,52+,53-,57+/m0/s1
SMILES Code
CO[C@@H]1C[C@@H](CC[C@H]1O)C[C@H]([C@@H]2CC([C@@H](/C=C([C@H]([C@@H](OC)C([C@@H](C[C@@H]([C@@H]3CC[C@H](/C=C([C@@H](OC)C[C@@H]4CC[C@H]([C@@](O4)(C(C(N5CCCC[C@H]5C(O2)=O)=O)=O)O)C)\C)ON3C6=CC=CC=C6)C)C)=O)O)\C)C)=O)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 1,023.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL