NSC-639828 is a benzoylphenylurea derivative and a main metabolite of HO-221 (NSC24548). This compound was first reported in patent EP 413977 (1991). This compound showed a board range of bioactivities including antitumor, anti-HCV infection; etc. NSC639828 inhibited the activities of E. coli DNA polymerase I and calf thymus DNA polymerase α. Excess DNA polymerase I or DNA polymerase α dramatically reduced the inhibition produced by these compds. NSC639828 also showed inhibitory effects of the synthesome-assocd.
MedKoo Cat#: 556056
Name: NSC639828
CAS#: 134742-26-0
Chemical Formula: C18H13BrClN5O3
Exact Mass: 460.9890
Molecular Weight: 462.69
Elemental Analysis: C, 46.73; H, 2.83; Br, 17.27; Cl, 7.66; N, 15.14; O, 10.37
The following data is based on the product molecular weight 462.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
