PHA-543613 dihydrochloride acts as a potent and selective agonist for the α7 subtype of neural nicotinic acetylcholine receptors, with a high level of brain penetration and good oral bioavailability. It is under development as a possible treatment for cognitive deficits in schizophrenia.
MedKoo Cat#: 471086
Name: PHA 543613 dihydrochloride
CAS#: 478148-58-2 (2HCl)
Chemical Formula: C15H19Cl2N3O2
Exact Mass:
Molecular Weight: 344.24
Elemental Analysis: C, 52.34; H, 5.56; Cl, 20.60; N, 12.21; O, 9.30
The following data is based on the product molecular weight 344.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
