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MedKoo Cat#: 465666 | Name: AMP-PNP tetralithium

Description:

WARNING: This product is for research use only, not for human or veterinary use.

AMP-PNP is a Kir6 (KATP) channel blocker, inhibiting fast axonal transport and stabilizing the interaction of membranous organelles with microtubules.

Chemical Structure

AMP-PNP tetralithium
AMP-PNP tetralithium
CAS#72957-42-7 (triphosphate tetralithium salt)

Theoretical Analysis

MedKoo Cat#: 465666

Name: AMP-PNP tetralithium

CAS#: 72957-42-7 (triphosphate tetralithium salt)

Chemical Formula: C10H13Li4N6O12P3

Exact Mass: 530.0444

Molecular Weight: 529.93

Elemental Analysis: C, 22.67; H, 2.47; Li, 5.24; N, 15.86; O, 36.23; P, 17.53

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
72957-42-7 (triphosphate tetralithium salt) 25612-73-1 (free base)
Synonym
AMP-PNP; AMPPNP; AMP PNP;
IUPAC/Chemical Name
tetralithium;[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]oxy-(phosphonatoamino)phosphinate
InChi Key
FDBDJIGGLGUOPP-KWIZKVQNSA-J
InChi Code
InChI=1S/C10H17N6O12P3.4Li/c11-8-5-9(13-2-12-8)16(3-14-5)10-7(18)6(17)4(27-10)1-26-31(24,25)28-30(22,23)15-29(19,20)21;;;;/h2-4,6-7,10,17-18H,1H2,(H,24,25)(H2,11,12,13)(H4,15,19,20,21,22,23);;;;/q;4*+1/p-4/t4-,6-,7-,10-;;;;/m1..../s1
SMILES Code
NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(NP(O[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O)O3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 529.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
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