MedKoo Cat#: 465588 | Name: Ac36Az9

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ac36Az9 is a potent, nontoxic, and highly selective BCRP inhibitor (EC50 = 1−15 nM).

Chemical Structure

Ac36Az9
Ac36Az9
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465588

Name: Ac36Az9

CAS#: unknown

Chemical Formula: C42H44N4O9

Exact Mass: 748.3108

Molecular Weight: 748.83

Elemental Analysis: C, 67.37; H, 5.92; N, 7.48; O, 19.23

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
Ac36Az9; Ac36 Az9; Ac36-Az9;
IUPAC/Chemical Name
methyl 3-(((2-(4-(2-(2-(2-(4-((benzyl(2-hydroxyethyl)amino)methyl)-1H-1,2,3-triazol-1-yl)ethoxy)ethoxy)ethoxy)phenyl)-4-oxo-4H-chromen-3-yl)oxy)methyl)benzoate
InChi Key
ITPZKJDGQFUXAL-UHFFFAOYSA-N
InChi Code
InChI=1S/C42H44N4O9/c1-50-42(49)34-11-7-10-32(26-34)30-54-41-39(48)37-12-5-6-13-38(37)55-40(41)33-14-16-36(17-15-33)53-25-24-52-23-22-51-21-19-46-29-35(43-44-46)28-45(18-20-47)27-31-8-3-2-4-9-31/h2-17,26,29,47H,18-25,27-28,30H2,1H3
SMILES Code
O=C(OC)C1=CC=CC(COC2=C(C3=CC=C(OCCOCCOCCN4N=NC(CN(CC5=CC=CC=C5)CCO)=C4)C=C3)OC6=C(C=CC=C6)C2=O)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 748.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wong ILK, Zhu X, Chan KF, Liu Z, Chan CF, Chow TS, Chong TC, Law MC, Cui J, Chow LMC, Chan TH. Flavonoid Monomers as Potent, Nontoxic, and Selective Modulators of the Breast Cancer Resistance Protein (ABCG2). J Med Chem. 2021 Oct 4. doi: 10.1021/acs.jmedchem.1c00779. Epub ahead of print. PMID: 34606270.