MedKoo Cat#: 415003 | Name: Pyroxamine Free Base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pyroxamine Free Base is an antihistamine and anticholinergic related to diphenylpyraline.

Chemical Structure

Pyroxamine Free Base
Pyroxamine Free Base
CAS#7009-68-9 (free base)

Theoretical Analysis

MedKoo Cat#: 415003

Name: Pyroxamine Free Base

CAS#: 7009-68-9 (free base)

Chemical Formula: C18H20ClNO

Exact Mass: 301.1233

Molecular Weight: 301.81

Elemental Analysis: C, 71.63; H, 6.68; Cl, 11.75; N, 4.64; O, 5.30

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
7009-68-9 (free base); 5560-75-8 (maleate)
Synonym
Pyroxamine Free Base; BRN0260129; BRN-0260129; BRN 0260129
IUPAC/Chemical Name
Pyrrolidine, 3-(p-chloro-alpha-phenylbenzyloxy)-1-methyl-
InChi Key
CMARNPIDSNAMJM-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H20ClNO/c1-20-12-11-17(13-20)21-18(14-5-3-2-4-6-14)15-7-9-16(19)10-8-15/h2-10,17-18H,11-13H2,1H3
SMILES Code
CN1CC(OC(C2=CC=CC=C2)C3=CC=C(Cl)C=C3)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 301.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: THOMAS JW. Pyroxamine: a clinical study of a new antihistamine. Ann Allergy. 1961 Jul;19:760-5. PMID: 13776501. 2: Smits PH, De Haan M, Maat C, Grivell LA. The complete sequence of a 33 kb fragment on the right arm of chromosome II from Saccharomyces cerevisiae reveals 16 open reading frames, including ten new open reading frames, five previously identified genes and a homologue of the SCO1 gene. Yeast. 1994 Apr;10 Suppl A:S75-80. doi: 10.1002/yea.320100010. PMID: 8091864.