Synonym
Piriqualone; B 169; B169; B-169; NSC96996; NSC-96996; NSC 96996
IUPAC/Chemical Name
2-(2-(2-Pyridyl)vinyl)-3-o-tolyl-4(3H)-quinazolinone
InChi Key
MYGZNGAHFWOCLI-BUHFOSPRSA-N
InChi Code
InChI=1S/C22H17N3O/c1-16-8-2-5-12-20(16)25-21(14-13-17-9-6-7-15-23-17)24-19-11-4-3-10-18(19)22(25)26/h2-15H,1H3/b14-13+
SMILES Code
O=C1N(C2=CC=CC=C2C)C(/C=C/C3=NC=CC=C3)=NC4=C1C=CC=C4
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
339.39
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Welch WM, Ewing FE, Huang J, Menniti FS, Pagnozzi MJ, Kelly K, Seymour PA, Guanowsky V, Guhan S, Guinn MR, Critchett D, Lazzaro J, Ganong AH, DeVries KM, Staigers TL, Chenard BL. Atropisomeric quinazolin-4-one derivatives are potent noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists. Bioorg Med Chem Lett. 2001 Jan 22;11(2):177-81. doi: 10.1016/s0960-894x(00)00622-3. PMID: 11206453. 2: Shah DS, Raghunath PR, Gupta AK, Makol R, Gulati OD. Neuromuscular blocking action of 2-(2-(3-pyridyl) vinyl)-3-0-tolyl-3, 4-dihydroquinazoline-4-one (SRC 909). Arch Int Pharmacodyn Ther. 1974 Jun;209(2):283-95. PMID: 4280276.
