Pinafide | CAS# 54824-20-3 | rodenticide and anti-protozoal agent

MedKoo Cat#: 414963 | Name: Pinafide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pinafide is a rodenticide and anti-protozoal agent. Pinafide shows strong cytostatic activity against both HeLa and KB cells and is moderately toxic to both mice and rats. It has been proved active against experimental tumors and shown to be inhibitor of two DNA viruses. Pinafide blocks cell growth by inhibiting DNA and RNA synthesis. It has been shown to bind to double-helical DNA by intercalation. Pinafide inhibited the activity of M. tuberculosis NAD⁺-dependent DNA ligase A at concentrations of 50 uM. At the chemical screening was found that pinafide inhibited B-Myb transcriptional activity in luciferase assays. The cross placental-barrier studies showed that 3H-pinafide was present in the 14-day fetuses.

Chemical Structure

Pinafide

CAS#54824-20-3

Theoretical Analysis

MedKoo Cat#: 414963

Name: Pinafide

CAS#: 54824-20-3

Chemical Formula: C18H17N3O4

Exact Mass: 339.1219

Molecular Weight: 339.35

Elemental Analysis: C, 63.71; H, 5.05; N, 12.38; O, 18.86

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Pinafide; NSC300289; NSC-300289; NSC 300289; BRN1553168; BRN-1553168; BRN 1553168

IUPAC/Chemical Name

3-Nitro-N-(2-(1-pyrrolidinyl)ethyl)naphthalimide

InChi Key

SDNHXDMIMAOSMD-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H17N3O4/c22-17-15-13-6-2-1-5-12(13)11-14(21(24)25)16(15)18(23)20(17)10-9-19-7-3-4-8-19/h1-2,5-6,11H,3-4,7-10H2

SMILES Code

O=[N+](C1=C2C(C(N(CCN3CCCC3)C2=O)=O)=C4C=CC=CC4=C1)[O-]

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 339.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

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