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MedKoo Cat#: 414908 | Name: Fenbutrazate HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fenbutrazate HCl is a psychostimulant used as an appetite suppressant under the trade names Cafilon, Filon, and Sabacid in Europe, Japan, and Hong Kong. It is a derivative of phenmetrazine and may function as a prodrug due to its similarity to phendimetrazine.

Chemical Structure

Fenbutrazate HCl
Fenbutrazate HCl
CAS#6474-85-7 (HCl)

Theoretical Analysis

MedKoo Cat#: 414908

Name: Fenbutrazate HCl

CAS#: 6474-85-7 (HCl)

Chemical Formula: C23H30ClNO3

Exact Mass: 403.1914

Molecular Weight: 403.95

Elemental Analysis: C, 68.39; H, 7.49; Cl, 8.78; N, 3.47; O, 11.88

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
6474-85-7 (HCl); 4378-36-3 (free base)
Synonym
Fenbutrazate hydrochloride; Fenbutrazate HCl; R381; R-381; R 381
IUPAC/Chemical Name
Benzeneacetic acid, alpha-ethyl-, 2-(3-methyl-2-phenyl-4-morpholinyl)ethyl ester, hydrochloride
InChi Key
QYNMGTGFHCYFIE-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H29NO3.ClH/c1-3-21(19-10-6-4-7-11-19)23(25)27-17-15-24-14-16-26-22(18(24)2)20-12-8-5-9-13-20;/h4-13,18,21-22H,3,14-17H2,1-2H3;1H
SMILES Code
O=C(OCCN1C(C)C(C2=CC=CC=C2)OCC1)C(CC)C3=CC=CC=C3.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 403.95 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Krautscheid Y, Senning CJ, Sartori SB, Singewald N, Schuster D, Stuppner H. Pharmacophore modeling, virtual screening, and in vitro testing reveal haloperidol, eprazinone, and fenbutrazate as neurokinin receptors ligands. J Chem Inf Model. 2014 Jun 23;54(6):1747-57. doi: 10.1021/ci500106z. Epub 2014 Jun 12. PMID: 24849814.