Synonym
Bromofenofos; AI3-29189; AI329189; AI3 29189; CCRIS5741; CCRIS-5741; CCRIS 5741
IUPAC/Chemical Name
(1,1'-Biphenyl)-2,2'-diol, 3,3',5,5'-tetrabromo-, mono(dihydrogen phosphate) (9CI)
InChi Key
MMYHZEDBTMXYAF-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H7Br4O5P/c13-5-1-7(11(17)9(15)3-5)8-2-6(14)4-10(16)12(8)21-22(18,19)20/h1-4,17H,(H2,18,19,20)
SMILES Code
OC1=C(Br)C=C(Br)C=C1C2=CC(Br)=CC(Br)=C2OP(O)(O)=O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
581.77
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Venturina VM, Alejandro MA, Baltazar CP, Abes NS, Mingala CN. Evidence of Fasciola spp. resistance to albendazole, triclabendazole and bromofenofos in water buffaloes (Bubalus bubalis). Ann Parasitol. 2015;61(4):283-9. doi: 10.17420/ap6104.20. PMID: 26878627.
2: Fujinuma K, Takeba K, Kamata K. [Concentration in plasma and excretion in milk of lactating cows after oral administration of tribromsalan, oxyclozanide and bromofenofos]. Shokuhin Eiseigaku Zasshi. 2006 Dec;47(6):249-53. Japanese. doi: 10.3358/shokueishi.47.249. PMID: 17228788.
3: Yoshimura H, Endoh YS. Plasma concentration and placental transfer of bromofenofos in rats. Toxicology. 1989 May 15;55(3):299-306. doi: 10.1016/0300-483x(89)90019-x. PMID: 2541520.
4: Yoshimura H, Nakamura M, Koeda T. Lack of mutagenicity of fasciolicides. Vet Res Commun. 1985 Apr;9(2):147-52. doi: 10.1007/BF02215138. PMID: 4002614.
5: Yoshimura H, Delatour P. Embryolethality of bromofenofos in rats. Toxicol Lett. 1986 Jun;31(3):243-7. doi: 10.1016/0378-4274(86)90132-3. PMID: 3014682.
6: Yoshimura H, Endoh YS, Hamamoto K. Pharmacokinetic data of bromofenofos in calves. Zentralbl Veterinarmed A. 1990 Sep;37(8):634-6. doi: 10.1111/j.1439-0442.1990.tb00955.x. PMID: 2174629.
7: Yoshimura H. Embryolethal and teratogenic effects of bromofenofos in rats. Arch Toxicol. 1987 Jun;60(4):319-24. doi: 10.1007/BF01234672. PMID: 2820351.
8: Yoshimura H. Comparative embryolethal effect of bromofenofos and dephosphate bromofenofos in rats. Arch Toxicol. 1987 Jun;60(4):325-7. doi: 10.1007/BF01234673. PMID: 2820352.
9: Takeba K, Itoh T, Matsumoto M, Nakazawa H. Determination of dephosphate bromofenofos in milk by liquid chromatography with electrochemical detection. J AOAC Int. 1994 Jul-Aug;77(4):904-8. PMID: 8069121.
10: Endoh YS, Yoshimura H, Sasaki N. High-performance liquid chromatographic determination of bromofenofos and its metabolite in rat plasma. J Chromatogr. 1988 Apr 8;426(1):202-6. doi: 10.1016/s0378-4347(00)81944-1. PMID: 2838496.
