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MedKoo Cat#: 601151 | Name: Honokiol
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Honokiol is a natural product, which is extracted from the bark or seed cones of the Magnolia tree have been widely used in traditional medicine in China, Korea, and Japan. Houpu has traditionally been used in Eastern medicine as analgesic and to treat anxiety and mood disorders. In China, magnolia bark is called Houpu and is most commonly taken from the Magnolia obovata and the Magnolia officinalis species. In the late 1990s, honokiol saw a revival in interest as a potent and highly tolerable antitumorigenic and neurotrophic compound.

Chemical Structure

Honokiol
Honokiol
CAS#35354-74-6

Theoretical Analysis

MedKoo Cat#: 601151

Name: Honokiol

CAS#: 35354-74-6

Chemical Formula: C18H18O2

Exact Mass: 266.1307

Molecular Weight: 266.33

Elemental Analysis: C, 81.17; H, 6.81; O, 12.01

Price and Availability

Size Price Availability Quantity
200mg USD 250.00 2 Weeks
500mg USD 450.00
1g USD 650.00
2g USD 950.00
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Related CAS #
No Data
Synonym
Honokiol, Houpa; Hnk
IUPAC/Chemical Name
2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol
InChi Key
FVYXIJYOAGAUQK-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
SMILES Code
OC1=CC=C(CC=C)C=C1C2=CC=C(O)C(CC=C)=C2
Appearance
solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO.
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 266.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Woodbury A, Yu SP, Wei L, García P. Neuro-modulating effects of honokiol: a review. Front Neurol. 2013 Sep 11;4:130. doi: 10.3389/fneur.2013.00130. eCollection 2013. Review. PubMed PMID: 24062717; PubMed Central PMCID: PMC3769637. 2: Kumar A, Kumar Singh U, Chaudhary A. Honokiol analogs: a novel class of anticancer agents targeting cell signaling pathways and other bioactivities. Future Med Chem. 2013 May;5(7):809-29. doi: 10.4155/fmc.13.32. Review. PubMed PMID: 23651094. 3: Tian W, Xu D, Deng YC. Honokiol, a multifunctional tumor cell death inducer. Pharmazie. 2012 Oct;67(10):811-6. Review. PubMed PMID: 23136712. 4: Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP. Honokiol: a novel natural agent for cancer prevention and therapy. Curr Mol Med. 2012 Dec;12(10):1244-52. Review. PubMed PMID: 22834827; PubMed Central PMCID: PMC3663139. 5: Shen JL, Man KM, Huang PH, Chen WC, Chen DC, Cheng YW, Liu PL, Chou MC, Chen YH. Honokiol and magnolol as multifunctional antioxidative molecules for dermatologic disorders. Molecules. 2010 Sep 16;15(9):6452-65. doi: 10.3390/molecules15096452. Review. PubMed PMID: 20877235. 6: Fried LE, Arbiser JL. Honokiol, a multifunctional antiangiogenic and antitumor agent. Antioxid Redox Signal. 2009 May;11(5):1139-48. doi: 10.1089/ARS.2009.2440. Review. PubMed PMID: 19203212; PubMed Central PMCID: PMC2842137.