MedKoo Cat#: 465461 | Name: ARN19702
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

ARN19702 is a potent rat NAAA inhibitor.

Chemical Structure

ARN19702
ARN19702
CAS#1971937-18-4

Theoretical Analysis

MedKoo Cat#: 465461

Name: ARN19702

CAS#: 1971937-18-4

Chemical Formula: C21H22FN3O3S2

Exact Mass: 447.1087

Molecular Weight: 447.54

Elemental Analysis: C, 56.36; H, 4.96; F, 4.25; N, 9.39; O, 10.72; S, 14.33

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,350.00 2 Weeks
500mg USD 2,650.00 2 Weeks
1g USD 3,850.00 2 Weeks
2g USD 6,250.00 2 Weeks
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Related CAS #
No Data
Synonym
ARN19702; ARN 19702; ARN-19702;
IUPAC/Chemical Name
(S)-(2-(ethylsulfonyl)phenyl)(4-(6-fluorobenzo[d]thiazol-2-yl)-2-methylpiperazin-1-yl)methanone
InChi Key
UKQOLPNYRVPCBM-AWEZNQCLSA-N
InChi Code
InChI=1S/C21H22FN3O3S2/c1-3-30(27,28)19-7-5-4-6-16(19)20(26)25-11-10-24(13-14(25)2)21-23-17-9-8-15(22)12-18(17)29-21/h4-9,12,14H,3,10-11,13H2,1-2H3/t14-/m0/s1
SMILES Code
FC1=CC2=C(N=C(N3C[C@H](C)N(C(C4=CC=CC=C4S(CC)(=O)=O)=O)CC3)S2)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 447.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Fotio Y, Sasso O, Ciccocioppo R, Piomelli D. Antinociceptive Profile of ARN19702, (2-Ethylsulfonylphenyl)-[(2S)-4-(6-fluoro-1,3-benzothiazol-2-yl)-2-met hylpiperazin-1-yl]methanone, a Novel Orally Active N-Acylethanolamine Acid Amidase Inhibitor, in Animal Models. J Pharmacol Exp Ther. 2021 Aug;378(2):70-76. doi: 10.1124/jpet.121.000674. Epub 2021 May 13. PMID: 33986036. 2: Fotio Y, Ciccocioppo R, Piomelli D. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol- preferring rats. Psychopharmacology (Berl). 2021 Jan;238(1):249-258. doi: 10.1007/s00213-020-05678-7. Epub 2020 Oct 10. PMID: 33037452; PMCID: PMC7796956.