MedKoo Cat#: 561767 | Name: FOL7185

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FOL7185 is an inhibitor of IspD and IspE enzymes isolated from bacteria.

Chemical Structure

FOL7185
FOL7185
CAS#5441-46-3

Theoretical Analysis

MedKoo Cat#: 561767

Name: FOL7185

CAS#: 5441-46-3

Chemical Formula: C13H12ClN5

Exact Mass: 273.0781

Molecular Weight: 273.72

Elemental Analysis: C, 57.04; H, 4.42; Cl, 12.95; N, 25.59

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
FOL7185; FOL-7185; FOL 7185;
IUPAC/Chemical Name
(4-Chloro-benzyl)-(1-methyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-amine
InChi Key
JMHQWHUUDRUTPU-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H12ClN5/c1-19-13-11(7-18-19)12(16-8-17-13)15-6-9-2-4-10(14)5-3-9/h2-5,7-8H,6H2,1H3,(H,15,16,17)
SMILES Code
CN1N=CC2=C(NCC3=CC=C(Cl)C=C3)N=CN=C21
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 273.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Goshu GM, Ghose D, Bain JM, Pierce PG, Begley DW, Hewitt SN, Udell HS, Myler PJ, Meganathan R, Hagen TJ. Synthesis and biological evaluation of pyrazolopyrimidines as potential antibacterial agents. Bioorg Med Chem Lett. 2015 Dec 15;25(24):5699-704. doi: 10.1016/j.bmcl.2015.10.096. PubMed PMID: 26584881; PubMed Central PMCID: PMC4764408.