Pd 158771 | CAS# 189152-50-9 | D2 and 5-HT1A agonist

MedKoo Cat#: 414811 | Name: Pd 158771

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Pd 158771 is a D2 and 5-HT1A agonist.

Chemical Structure

Pd 158771

CAS#189152-50-9

Theoretical Analysis

MedKoo Cat#: 414811

Name: Pd 158771

CAS#: 189152-50-9

Chemical Formula: C22H31N5

Exact Mass: 365.2579

Molecular Weight: 365.53

Elemental Analysis: C, 72.29; H, 8.55; N, 19.16

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Pd 158771; Pd158771; Pd-158771

IUPAC/Chemical Name

2-Pyrimidinamine, N-(4-(2-(4-phenyl-1-piperazinyl)ethyl)cyclohexyl)-, trans-

InChi Key

OUUMPVSFLSOGJZ-MXVIHJGJSA-N

InChi Code

InChI=1S/C22H31N5/c1-2-5-21(6-3-1)27-17-15-26(16-18-27)14-11-19-7-9-20(10-8-19)25-22-23-12-4-13-24-22/h1-6,12-13,19-20H,7-11,14-18H2,(H,23,24,25)/t19-,20-

SMILES Code

C1(N[C@H]2CC[C@H](CCN3CCN(C4=CC=CC=C4)CC3)CC2)=NC=CC=N1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 365.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Corbin AE, Meltzer LT, Ninteman FW, Wiley JN, Christoffersen CL, Wustrow DJ, Wise LD, Pugsley TA, Heffner TG. PD 158771, a potential antipsychotic agent with D2/D3 partial agonist and 5-HT(1A) agonist actions. II. Preclinical behavioral effects. Neuropharmacology. 2000 Apr 27;39(7):1211-21. doi: 10.1016/s0028-3908(99)00214-2. PMID: 10760363. 2: Akunne HC, Zoski KT, Davis MD, Cooke LW, Meltzer LT, Whetzel SZ, Shih YH, Wustrow DJ, Wise LD, MacKenzie RG, Georgic LM, Heffner TG, Pugsley TA. PD 158771, a potential antipsychotic agent with D(2)/D(3) partial agonist and 5-HT(1A) agonist actions. I. Neurochemical effects. Neuropharmacology. 2000 Apr 27;39(7):1197-210. doi: 10.1016/s0028-3908(99)00224-5. PMID: 10760362. 3: Wustrow D, Belliotti T, Glase S, Kesten SR, Johnson D, Colbry N, Rubin R, Blackburn A, Akunne H, Corbin A, Davis MD, Georgic L, Whetzel S, Zoski K, Heffner T, Pugsley T, Wise L. Aminopyrimidines with high affinity for both serotonin and dopamine receptors. J Med Chem. 1998 Feb 26;41(5):760-71. doi: 10.1021/jm9707378. PMID: 9513604.