MedKoo Cat#: 465348 | Name: (-)-Gomisin M1

Description:

WARNING: This product is for research use only, not for human or veterinary use.

(-)-Gomisin M1 is a natural modulator of miRNA biogenesis, inhibiting the proliferation, migration, and invasion of hepatocellular carcinoma (HCC) cells.

Chemical Structure

(-)-Gomisin M1
(-)-Gomisin M1
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465348

Name: (-)-Gomisin M1

CAS#: unknown

Chemical Formula: C22H26O6

Exact Mass: 386.1729

Molecular Weight: 386.44

Elemental Analysis: C, 68.38; H, 6.78; O, 24.84

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
(-)-Gomisin M1; (-) Gomisin M1;
IUPAC/Chemical Name
(6R,7R)-2,3,13-trimethoxy-6,7-dimethyl-5,6,7,8-tetrahydrobenzo[3',4']cycloocta[1',2':4,5]benzo[1,2-d][1,3]dioxol-1-ol
InChi Key
OGJPBGDUYKEQLA-VXGBXAGGSA-N
InChi Code
InChI=1S/C22H26O6/c1-11-6-13-8-15(24-3)20(25-4)19(23)17(13)18-14(7-12(11)2)9-16-21(22(18)26-5)28-10-27-16/h8-9,11-12,23H,6-7,10H2,1-5H3/t11-,12-/m1/s1
SMILES Code
C[C@@H]1CC(C=C2OCOC2=C3OC)=C3C(C(C[C@H]1C)=C4)=C(O)C(OC)=C4OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 386.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Zhou Z, Li Y, Ma X, Cao B, Peng T, Sheng Y, Peng H, Li R, Cao Y, Xi R, Li F, Wang M, Sun H, Zhang G, Zhang H, Hu K, Xiao W, Wang F. Identification of a Novel TAR RNA-Binding Protein 2 Modulator with Potential Therapeutic Activity against Hepatocellular Carcinoma. J Med Chem. 2021 Jun 10;64(11):7404-7421. doi: 10.1021/acs.jmedchem.1c00018. Epub 2021 May 26. PMID: 34038111. 2: Poornima B, Kumar DA, Siva B, Venkanna A, Vadaparthi PR, Kumar K, Tiwari AK, Babu KS. Advanced glycation end-products inhibitors isolated from Schisandra grandiflora. Nat Prod Res. 2016;30(4):493-6. doi: 10.1080/14786419.2015.1024117. Epub 2015 Mar 27. PMID: 25812677. 3: Chen M, Kilgore N, Lee KH, Chen DF. Rubrisandrins A and B, lignans and related anti-HIV compounds from Schisandra rubriflora. J Nat Prod. 2006 Dec;69(12):1697-701. doi: 10.1021/np060239e. PMID: 17190445. 4: Rui T, Lian-Niang L, Qicheng F. Studies on the Chemical Constituents of Kadsura longipedunculata: Isolation and Structure Elucidation of Five New Lignans. Planta Med. 1984 Oct;50(5):414-7. doi: 10.1055/s-2007-969751. PMID: 17340342.