MedKoo Cat#: 414680 | Name: Hydroxyprocaine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hydroxyprocaine was invented as a local anesthetic drug that possessed the antibacterial properties.

Chemical Structure

Hydroxyprocaine
Hydroxyprocaine
CAS#487-53-6

Theoretical Analysis

MedKoo Cat#: 414680

Name: Hydroxyprocaine

CAS#: 487-53-6

Chemical Formula: C13H20N2O3

Exact Mass: 252.1474

Molecular Weight: 252.31

Elemental Analysis: C, 61.88; H, 7.99; N, 11.10; O, 19.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Hydroxyprocaine; NSC12480; NSC-12480; NSC 12480
IUPAC/Chemical Name
2-Diethylaminoethyl 4-aminosalicylate
InChi Key
GHSCYMOJHVOGDJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H20N2O3/c1-3-15(4-2)7-8-18-13(17)11-6-5-10(14)9-12(11)16/h5-6,9,16H,3-4,7-8,14H2,1-2H3
SMILES Code
OC1=CC(N)=CC=C1C(OCCN(CC)CC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 252.31 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: HEKNEBY M. Oxyprocain forte, et nytt lokalanestetikum til bruk i tannlegepraksäs [2-Hydroxyprocaine, a new local anesthetic for dental use]. Nor Tannlaegeforen Tid. 1954 Sep;64(7):283-8. Norwegian. PMID: 13214576. 2: SCHALLER KF, SERIE C. Oxyprocain-Penicillin in der Lepratherapie [Hydroxyprocaine penicillin therapy of leprosy]. Z Haut Geschlechtskr. 1958 Dec 15;25(12):340-6. German. PMID: 13625789. 3: Schmidt AC, Schwarz I. Solid-state characterization of non-stoichiometric hydrates of ester-type local anaesthetics. Part XI. Crystal polymorphism of local anaesthetic drugs. Int J Pharm. 2006 Aug 31;320(1-2):4-13. doi: 10.1016/j.ijpharm.2006.04.017. Epub 2006 May 3. PMID: 16857329. 4: TRAPPMANN R. A new remedy for leprosy, hydroxyprocaine-penicillin. Int J Lepr. 1961 Jan-Mar;29:46-55. PMID: 13777898. 5: HARNISCH H, LAMMERS T. Die klinische Bedeutung der antibakteriellen Eigenschaften von Novocain und Oxyprocain [Clinical significance of antibacterial properties novocaine and hydroxyprocaine]. Arzneimittelforschung. 1953 Nov;3(11):589-91. Undetermined Language. PMID: 13126004. 6: GEDDES IC. Local anaesthetic properties and toxicity of hydroxyprocaine and hydroxyamethocaine. Br J Anaesth. 1956 Feb;28(2):55-66. doi: 10.1093/bja/28.2.55. PMID: 13293283. 7: LIEBERMEISTER K, RUOF H, HUTTNER HJ. Zum Wirkungscharakter von Oxyprocainpenicillin auf Tuberkelbakterien im Brutei [Effect of hydroxyprocaine penicillin on tubercle bacteria in incubated egg]. Z Hyg Infektionskr. 1954;140(5):442-7. German. PMID: 14360235. 8: NAWROCKI G. Antibiotic therapy of tuberculosis with hydroxyprocaine penicillin and paratebin. Dtsch Gesundheitsw. 1954 Apr 29;9(17):532-6. English, German. PMID: 13191063. 9: HIRSCH E, HOLLER W. Die klinische Bedeutung der antibakteriellen Eigenschaften von Novocain und Oxyprocain [Clinical significance of antibacterial properties of novocaine and hydroxyprocaine]. Arzneimittelforschung. 1953 Nov;3(11):592. Undetermined Language. PMID: 13126005. 10: RADENBACH KL, KUNEKE S, LIEBERMEISTER K. Kritische Untersuchungen über Oxyprocainpenicillin und Paratebin [Critical studies on hydroxyprocaine penicillin and paratebin]. Med Monatsschr. 1953 Sep;7(9):555-62. Undetermined Language. PMID: 13119328.