IUN-70219 | CAS#331770-21-9 | ATP-competitive inhibitor

MedKoo Cat#: 464574 | Name: IUN-70219

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Description:

WARNING: This product is for research use only, not for human or veterinary use.

IUN-70219 is a novel selective and ATP-competitive inhibitor of Aurora kinases (IC50 = 310 nM and 240 nM for Aurora A and B, respectively). This product has no formal name at the moment. For the convenience of communication, a temporary code name was therefore proposed according to MedKoo Chemical Nomenclature (see web page: https://www.medkoo.com/page/naming).

Chemical Structure

IUN-70219

CAS#331770-21-9

Theoretical Analysis

MedKoo Cat#: 464574

Name: IUN-70219

CAS#: 331770-21-9

Chemical Formula: C23H20N4O3

Exact Mass: 400.1535

Molecular Weight: 400.44

Elemental Analysis: C, 68.99; H, 5.03; N, 13.99; O, 11.99

Price and Availability

Size	Price	Availability	Quantity
1mg	USD 300.00	2 Weeks
5mg	USD 700.00	2 Weeks

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Related CAS #

No Data

Synonym

IUN-70219; IUN70219; IUN 70219; Aurora Kinase Inhibitor II; Aurora Kinase Inhibitor-II;

IUPAC/Chemical Name

N-(4-((6,7-dimethoxyquinazolin-4-yl)amino)phenyl)benzamide

InChi Key

IMYVCWQAHSYYOO-UHFFFAOYSA-N

InChi Code

InChI=1S/C23H20N4O3/c1-29-20-12-18-19(13-21(20)30-2)24-14-25-22(18)26-16-8-10-17(11-9-16)27-23(28)15-6-4-3-5-7-15/h3-14H,1-2H3,(H,27,28)(H,24,25,26)

SMILES Code

O=C(NC1=CC=C(NC2=C3C=C(OC)C(OC)=CC3=NC=N2)C=C1)C4=CC=CC=C4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

	Solvent	mg/mL	mM
Solubility
	DMF	0.3	0.62
	DMF:PBS(pH7.2) (1:2)	0.3	0.82
	DMSO	2.5	6.20

Note: There can be variations in solubility for the same chemical from different vendors or different batches from the same vendor. The following factors can affect the solubility of the same chemical: solvent used for crystallization, residual solvent content, polymorphism, salt versus free form, degree of hydration, solvent temperature. Please use the solubility data as a reference only. Warming and sonication will facilitate dissolving. Still have questions? Please contact our Technical Support scientists.

Preparing Stock Solutions

The following data is based on the product molecular weight 400.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.