Oxarbazole | CAS# 35578-20-2 | Anti-Asthmatic

MedKoo Cat#: 414664 | Name: Oxarbazole

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Oxarbazole is an antagonist of slow-reacting substance of anaphylaxis.

Chemical Structure

Oxarbazole

CAS#35578-20-2

Theoretical Analysis

MedKoo Cat#: 414664

Name: Oxarbazole

CAS#: 35578-20-2

Chemical Formula: C21H19NO4

Exact Mass: 349.1314

Molecular Weight: 349.39

Elemental Analysis: C, 72.19; H, 5.48; N, 4.01; O, 18.32

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Oxarbazole; Win34284; Win-34284; Win 34284

IUPAC/Chemical Name

1H-Carbazole-3-carboxylic acid, 9-benzoyl-2,3,4,9-tetrahydro-6-methoxy-

InChi Key

ZNHCPKKNDKCPDG-UHFFFAOYSA-N

InChi Code

InChI=1S/C21H19NO4/c1-26-15-8-10-19-17(12-15)16-11-14(21(24)25)7-9-18(16)22(19)20(23)13-5-3-2-4-6-13/h2-6,8,10,12,14H,7,9,11H2,1H3,(H,24,25)

SMILES Code

O=C(C1CCC(N(C(C2=CC=CC=C2)=O)C3=C4C=C(OC)C=C3)=C4C1)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 349.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Benziger D, Dorrbecker S, Goehl T, Edelson J. Absorption and disposition of oxarbazole in man and laboratory animals. Drug Metab Dispos. 1978 Jan- Feb;6(1):8-15. PMID: 23278. 2: Edelson J, Benziger DP. Disposition of a series of tetrahydrocarbazoles. Drug Metab Rev. 1980;11(2):263-89. doi: 10.3109/03602538008994027. PMID: 7011760. 3: Mielens ZE. Evaluation of the antiasthmatic potential of oxarbazole in guinea pigs. Pharmacology. 1978;17(6):323-9. doi: 10.1159/000136873. PMID: 733892. 4: Furukawa CT. Other pharmacologic agents that may affect bronchial hyperreactivity. J Allergy Clin Immunol. 1984 May;73(5 Pt 2):693-8. doi: 10.1016/0091-6749(84)90308-7. PMID: 6143771. 5: Mielens ZE, Ferguson EW, Ferrari RA. Pharmacologic characterization of immune complex induced bronchoconstriction in guinea pigs. Agents Actions. 1981 Dec;11(6-7):673-8. doi: 10.1007/BF01978788. PMID: 6462038. 6: Mielens ZE. The effects of antiasthmatic drugs against immune complex-induced bronchoconstriction in anesthetized dogs. Pharmacology. 1979;18(6):311-8. doi: 10.1159/000137271. PMID: 115021.