Org 33201 | CAS# 148714-92-5 | potent aromatase inhibitor

MedKoo Cat#: 414615 | Name: Org 33201

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Org 33201 is a potent aromatase inhibitor.

Chemical Structure

Org 33201

CAS#148714-92-5

Theoretical Analysis

MedKoo Cat#: 414615

Name: Org 33201

CAS#: 148714-92-5

Chemical Formula: C21H28N2S

Exact Mass: 340.1973

Molecular Weight: 340.53

Elemental Analysis: C, 74.07; H, 8.29; N, 8.23; S, 9.41

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Org 33201; Org33201; Org-33201

IUPAC/Chemical Name

1-((3alpha-Ethyl-9-(ethylthio)-2,3,3alpha,4,5,6-hexahydro-1H-phenalen-2-yl)methyl)-1H-imidazole

InChi Key

MNNIVUMUBYKRKM-ADKAHSJRSA-N

InChi Code

InChI=1S/C21H28N2S/c1-3-17-16(13-23-11-10-22-14-23)12-19-20(24-4-2)9-8-15-6-5-7-18(17)21(15)19/h8-11,14,16-18H,3-7,12-13H2,1-2H3/t16?,17-,18?/m0/s1

SMILES Code

CCSC1=CC=C2CCCC3[C@@H](CC)C(CN4C=CN=C4)CC1=C32

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 340.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Geelen JA, Loozen HJ, Deckers GH, de Leeuw R, Kloosterboer HJ, Lamberts SW. Org 33201: a new highly selective orally active aromatase inhibitor. J Steroid Biochem Mol Biol. 1993 Mar;44(4-6):681-2. doi: 10.1016/0960-0760(93)90281-z. PMID: 8476784. 2: de Gooyer ME, Oppers-Tiemissen HM, Leysen D, Verheul HA, Kloosterboer HJ. Tibolone is not converted by human aromatase to 7alpha-methyl-17alpha- ethynylestradiol (7alpha-MEE): analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS. Steroids. 2003 Mar;68(3):235-43. doi: 10.1016/s0039-128x(02)00184-8. PMID: 12628686.