MedKoo Cat#: 584925 | Name: OPC 18692

Description:

WARNING: This product is for research use only, not for human or veterinary use.

OPC 18692 is a metabolite of Vesnarinone, a positive inotropic drug developed for congestive heart failure.

Chemical Structure

OPC 18692
OPC 18692
CAS#211369-52-7

Theoretical Analysis

MedKoo Cat#: 584925

Name: OPC 18692

CAS#: 211369-52-7

Chemical Formula: C22H23N3O4

Exact Mass: 393.1689

Molecular Weight: 393.44

Elemental Analysis: C, 67.16; H, 5.89; N, 10.68; O, 16.27

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
OPC 18692; OPC18692; OPC-18692
IUPAC/Chemical Name
Pyrazine, 1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydro-4-(1,2,3,4-tetrahydro-2-oxo-6-quinolinyl)-
InChi Key
MMJDLDDXKDBQTO-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H23N3O4/c1-28-19-7-3-16(14-20(19)29-2)22(27)25-11-9-24(10-12-25)17-5-6-18-15(13-17)4-8-21(26)23-18/h3,5-7,9,11,13-14H,4,8,10,12H2,1-2H3,(H,23,26)
SMILES Code
O=C1NC2=C(C=C(N3CCN(C(C4=CC=C(OC)C(OC)=C4)=O)C=C3)C=C2)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>3 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 393.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Sekar KS, Bramer SL. Extended application of an LC-MS/MS method for the analysis of vesnarinone and its metabolites in human urine and dialysate fluid. J Pharm Biomed Anal. 2003 Nov 24;33(4):711-7. PubMed PMID: 14623597. 2: Frye RF, Tammara B, Cowart TD, Bramer SL. Effect of disulfiram-mediated CYP2E1 inhibition on the disposition of vesnarinone. J Clin Pharmacol. 1999 Nov;39(11):1177-83. PubMed PMID: 10579149. 3: Wandel C, Lang CC, Cowart DC, Girard AF, Bramer S, Flockhart DA, Wood AJ. Effect of CYP3A inhibition on vesnarinone metabolism in humans. Clin Pharmacol Ther. 1998 May;63(5):506-11. PubMed PMID: 9630823.