MedKoo Cat#: 414551 | Name: Piperilate HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Piperilate HCl is an antispasmodic, antimuscarinic agent. It is a muscarinic cholinergic receptor antagonist.

Chemical Structure

Piperilate HCl
Piperilate HCl
CAS#4544-15-4 (HCl)

Theoretical Analysis

MedKoo Cat#: 414551

Name: Piperilate HCl

CAS#: 4544-15-4 (HCl)

Chemical Formula: C21H26ClNO3

Exact Mass:

Molecular Weight: 375.89

Elemental Analysis: C, 67.10; H, 6.97; Cl, 9.43; N, 3.73; O, 12.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
4544-15-4 (HCl);
Synonym
Piperilate hydrochloride; Piperilate HCl; Phorbic; NSC30793; NSC-30793; NSC 30793; Pinate
IUPAC/Chemical Name
Benzeneacetic acid, alpha-hydroxy-alpha-phenyl-, 2-(1-piperidinyl)ethyl ester, hydrochloride (9CI)
InChi Key
ZJVKLBBPLUXEAC-UHFFFAOYSA-N
InChi Code
InChI=1S/C21H25NO3.ClH/c23-20(25-17-16-22-14-8-3-9-15-22)21(24,18-10-4-1-5-11-18)19-12-6-2-7-13-19;/h1-2,4-7,10-13,24H,3,8-9,14-17H2;1H
SMILES Code
O=C(OCCN1CCCCC1)C(C2=CC=CC=C2)(O)C3=CC=CC=C3.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 375.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: PIPERIDOLATE hydrochloride. J Am Med Assoc. 1957 May 18;164(3):281. PMID: 13415981. 2: Attwood D. Aggregation of antiacetylcholine drugs in aqueous solution: micellar properties of some diphenylmethane derivatives. J Pharm Pharmacol. 1976 May;28(5):407-9. doi: 10.1111/j.2042-7158.1976.tb04643.x. PMID: 6747. 3: HARA M, HARBERG FJ, HUDSON LH. Antifibrillatory action of piperidolate hydrochloride (dactil) in hypothermia. AMA Arch Surg. 1957 Nov;75(5):780-4. doi: 10.1001/archsurg.1957.01280170090040. PMID: 13468923. 4: SALLE J. Action du chlorhydrate de l'ester diphénylacétique de la N-éthyl hydroxy-3-pipéridine (1087 AN) sur le jeu du sphincter d'Oddi, chez le cobaye [Effect of piperidolate hydrochloride on Oddi's sphincter function in the guinea pig]. C R Seances Soc Biol Fil. 1958;152(4):575-8. French. PMID: 13597345. 5: FILIPAZZI A, LOSAPIO M. [Considerations on ventricular fibrillation in hypothermia and on the anti-fibrillating action of piperidolate hydrochloride]. Riv Patol Clin. 1961 Dec;16:926-30. Italian. PMID: 13892861. 6: Kelkar MS. Atropine substitutes and the writhing syndrome in mice. Arch Int Pharmacodyn Ther. 1977 Sep;229(1):133-7. PMID: 931459.