Synonym
OC 5186; OC5186; OC-5186
IUPAC/Chemical Name
(Z)-7-(2-((S,E)-3-hydroxyoct-1-en-1-yl)-5-oxocyclopent-1-en-1-yl)hept-5-enoic acid compound with (R)-5-((S)-1,2-dihydroxyethyl)-3,4-dihydroxyfuran-2(5H)-one (1:1)
InChi Key
PAZBJQRIQDIEQH-UBKHKVECSA-N
InChi Code
InChI=1S/C20H30O4.C6H8O6/c1-2-3-6-9-17(21)14-12-16-13-15-19(22)18(16)10-7-4-5-8-11-20(23)24;7-1-2(8)5-3(9)4(10)6(11)12-5/h4,7,12,14,17,21H,2-3,5-6,8-11,13,15H2,1H3,(H,23,24);2,5,7-10H,1H2/b7-4-,14-12+;/t17-;2-,5+/m00/s1
SMILES Code
CCCCC[C@@H](/C=C/C1=C(C(CC1)=O)C/C=C\CCCC(O)=O)O.OC[C@@H]([C@H]2OC(C(O)=C2O)=O)O
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
510.58
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Tokuka A, Tanaka A, Fujita T, Hayashi M, Kitai T, Yamaoka Y, Ozawa K, Ohnishi ST. Protective effect of a prostaglandin oligomer on liver mitochondria in situ: time-shared measurements of fluorescence and reflectance in the cold-preserved rat liver. Transpl Int. 1992 Sep;5(4):193-6. doi: 10.1007/BF00336068. PMID: 1418308.
2: Chandra S, Ohnishi ST, Dhawan BN. Reversal of chloroquine resistance in murine malaria parasites by prostaglandin derivatives. Am J Trop Med Hyg. 1993 May;48(5):645-51. doi: 10.4269/ajtmh.1993.48.645. PMID: 8517483.
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4: Sakamoto A, Ohnishi ST, Ohnishi T, Ogawa R. Protective effect of a new anti- oxidant on the rat brain exposed to ischemia-reperfusion injury: inhibition of free radical formation and lipid peroxidation. Free Radic Biol Med. 1991;11(4):385-91. doi: 10.1016/0891-5849(91)90155-v. PMID: 1665837.
5: Hidaka S, Morita N, Ohnishi ST, Oga Y, Abe K. Inhibitory effect of prostaglandin oligomeric derivatives on 9,10-dimethyl-1,2-benzanthracene-induced hamster lingual carcinomas. Cancer Lett. 1992 Jan 10;61(2):171-6. doi: 10.1016/0304-3835(92)90176-v. PMID: 1730141.
