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MedKoo Cat#: 504212 | Name: TPT197 HCl
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

TPT-197 is a thiophene thiourea derivative with molecule weight 197 in free base form. There is no formal name yet, we temporally call this molecule as TPT-197. Please also see similar products: TPT-197; TPT-260; TPT-172.

Chemical Structure

TPT197 HCl
TPT197 HCl
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 504212

Name: TPT197 HCl

CAS#: unknown

Chemical Formula: C7H8ClN3S2

Exact Mass:

Molecular Weight: 233.73

Elemental Analysis: C, 35.97; H, 3.45; Cl, 15.17; N, 17.98; S, 27.43

Price and Availability

Size Price Availability Quantity
5mg USD 190.00 Ready to ship
10mg USD 350.00 Ready to ship
25mg USD 750.00 Ready to ship
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Related CAS #
No Data
Synonym
TPT197; TPT197; TPT 197 HCl, Thiophene-thiourea derivative
IUPAC/Chemical Name
(5-cyanothiophen-2-yl)methyl carbamimidothioate hydrochloride.
InChi Key
SEXFLLDORYSNIB-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H7N3S2.ClH/c8-3-5-1-2-6(12-5)4-11-7(9)10;/h1-2H,4H2,(H3,9,10);1H
SMILES Code
NC(SCC1=CC=C(C#N)S1)=N.[H]Cl
Appearance
white to off-white solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in water
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
 Dr. Petskso's research recently published a new paper   (Nat Chem Biol. 2014 Jun;10(6):443-9. doi: 10.1038/nchembio.1508.). TPT-260  and TPT-172 were supplied by MedKoo Biosciences.  Supplementary Text and Figures (1,865 KB) can be download for free.         

Preparing Stock Solutions

The following data is based on the product molecular weight 233.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mecozzi VJ, Berman DE, Simoes S, Vetanovetz C, Awal MR, Patel VM, Schneider RT, Petsko GA, Ringe D, Small SA. Pharmacological chaperones stabilize retromer to limit APP processing. Nat Chem Biol. 2014 Jun;10(6):443-9. doi: 10.1038/nchembio.1508. Epub 2014 Apr 20. PubMed PMID: 24747528.