MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 414391 | Name: Fluperamide HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fluperamide HCl is an antidiarrheal agent

Chemical Structure

Fluperamide HCl
Fluperamide HCl
CAS#34552-82-4 (HCl)

Theoretical Analysis

MedKoo Cat#: 414391

Name: Fluperamide HCl

CAS#: 34552-82-4 (HCl)

Chemical Formula: C30H33Cl2F3N2O2

Exact Mass:

Molecular Weight: 581.50

Elemental Analysis: C, 61.97; H, 5.72; Cl, 12.19; F, 9.80; N, 4.82; O, 5.50

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
34552-82-4 (HCl); 53179-10-5 (free base)
Synonym
Fluperamide hydrochloride; Fluperamide HCl; NIH 8636; NIH 8715; UM 866; UM 900
IUPAC/Chemical Name
1-Piperidinebutanamide, 4-(4-chloro-3-(trifluoromethyl)phenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-, monohydrochloride
InChi Key
GEWHMNRKXIVZJF-UHFFFAOYSA-N
InChi Code
InChI=1S/C30H32ClF3N2O2.ClH/c1-35(2)27(37)29(22-9-5-3-6-10-22,23-11-7-4-8-12-23)17-20-36-18-15-28(38,16-19-36)24-13-14-26(31)25(21-24)30(32,33)34;/h3-14,21,38H,15-20H2,1-2H3;1H
SMILES Code
O=C(N(C)C)C(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3CCC(O)(C4=CC=C(Cl)C(C(F)(F)F)=C4)CC3.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 581.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Megens AA, Canters LL, Awouters FH, Niemegeers CJ. Normalization of small intestinal propulsion with loperamide-like antidiarrheals in rats. Eur J Pharmacol. 1990 Mar 27;178(3):357-64. PubMed PMID: 2340864. 2: Reynolds IJ, Gould RJ, Snyder SH. Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects. J Pharmacol Exp Ther. 1984 Dec;231(3):628-32. PubMed PMID: 6502516. 3: Farrington H, Mendelsohn F, Chan S, Reinlib L, Guggino SE. Strychnine-binding proteins in intestinal cells: novel brucine binding site with binding affinities for alkaloids. J Pharmacol Exp Ther. 1994 Nov;271(2):1074-9. PubMed PMID: 7525935.