MedKoo Cat#: 577084 | Name: Betahistine mesylate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Betahistine mesylate is a biochemical that may be useful in the treatment of peripheral vertigo.

Chemical Structure

Betahistine mesylate
Betahistine mesylate
CAS#54856-23-4 (mesylate)

Theoretical Analysis

MedKoo Cat#: 577084

Name: Betahistine mesylate

CAS#: 54856-23-4 (mesylate)

Chemical Formula: C10H20N2O6S2

Exact Mass: 328.0763

Molecular Weight: 328.40

Elemental Analysis: C, 36.57; H, 6.14; N, 8.53; O, 29.23; S, 19.53

Price and Availability

Size Price Availability Quantity
5g USD 250.00 2 Weeks
25g USD 550.00 2 Weeks
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Synonym
Betahistine mesilate; Betahistine mesylate; Extovyl; Meginalisk; Melopat; Merislon; Riptonin
IUPAC/Chemical Name
N-methyl-2-(pyridin-2-yl)ethan-1-amine dimethanesulfonate
InChi Key
ZBJJDYGJCNTNTH-UHFFFAOYSA-N
InChi Code
InChI=1S/C8H12N2.2CH4O3S/c1-9-7-5-8-4-2-3-6-10-8;2*1-5(2,3)4/h2-4,6,9H,5,7H2,1H3;2*1H3,(H,2,3,4)
SMILES Code
CNCCC1=NC=CC=C1.CS(=O)(O)=O.CS(=O)(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 328.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Murdin L, Hussain K, Schilder AG. Betahistine for symptoms of vertigo. Cochrane Database Syst Rev. 2016 Jun 21;2016(6):CD010696. doi: 10.1002/14651858.CD010696.pub2. PMID: 27327415; PMCID: PMC7388750. 2. Ramos Alcocer R, Ledezma Rodríguez JG, Navas Romero A, Cardenas Nuñez JL, Rodríguez Montoya V, Deschamps JJ, Liviac Ticse JA. Use of betahistine in the treatment of peripheral vertigo. Acta Otolaryngol. 2015;135(12):1205-11. doi: 10.3109/00016489.2015.1072873. Epub 2015 Aug 6. PMID: 26245698. 3. Adrion C, Fischer CS, Wagner J, Gürkov R, Mansmann U, Strupp M; BEMED Study Group. Efficacy and safety of betahistine treatment in patients with Meniere's disease: primary results of a long term, multicentre, double blind, randomised, placebo controlled, dose defining trial (BEMED trial). BMJ. 2016 Jan 21;352:h6816. doi: 10.1136/bmj.h6816. PMID: 26797774; PMCID: PMC4721211.