MedKoo Cat#: 577067 | Name: Medetomidine free base
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Medetomidine, also known as MPV-785, is a synthetic drug used as both a surgical anesthetic and analgesic. It is an alpha-2 adrenergic agonist that can be administered as an intravenous drug solution with sterile water. It is currently approved for dogs in the United States. Medetomidine is a racemic mixture of two stereoisomers; dexmedetomidine is the isomer with more useful effects, and is now marketed as Dexdomitor. Medetomidine can be used as an antifouling substance in marine paint. It is mainly effective against barnacles.

Chemical Structure

Medetomidine free base
Medetomidine free base
CAS#86347-14-0 (free base)

Theoretical Analysis

MedKoo Cat#: 577067

Name: Medetomidine free base

CAS#: 86347-14-0 (free base)

Chemical Formula: C13H16N2

Exact Mass: 200.1313

Molecular Weight: 200.28

Elemental Analysis: C, 77.96; H, 8.05; N, 13.99

Price and Availability

Size Price Availability Quantity
1g USD 450.00 2 Weeks
2g USD 750.00 2 Weeks
5g USD 1,350.00 2 Weeks
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Synonym
Medetomidine; MPV-785; MPV 785; MPV785;
IUPAC/Chemical Name
1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-
InChi Key
CUHVIMMYOGQXCV-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)
SMILES Code
CC(c1c[nH]cn1)c2cccc(C)c2C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 200.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Murrell JC, Hellebrekers LJ. Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog. Vet Anaesth Analg. 2005 May;32(3):117-27. Review. PubMed PMID: 15877658. 2: Sinclair MD. A review of the physiological effects of alpha2-agonists related to the clinical use of medetomidine in small animal practice. Can Vet J. 2003 Nov;44(11):885-97. Review. PubMed PMID: 14664351; PubMed Central PMCID: PMC385445. 3: Cullen LK. Medetomidine sedation in dogs and cats: a review of its pharmacology, antagonism and dose. Br Vet J. 1996 Sep;152(5):519-35. Review. PubMed PMID: 8885463. 4: Pertovaara A. Antinociception induced by alpha-2-adrenoceptor agonists, with special emphasis on medetomidine studies. Prog Neurobiol. 1993 Jun;40(6):691-709. Review. PubMed PMID: 8097888. 5: Schmidt-Oechtering GU, Becker K. [Old and new alpha 2-adrenoceptor agonists. 1. Xylazine and medetomidine]. Tierarztl Prax. 1992 Oct;20(5):447-58. Review. German. PubMed PMID: 1359676. 6: Vainio O. Introduction to the clinical pharmacology of medetomidine. Acta Vet Scand Suppl. 1989;85:85-8. Review. PubMed PMID: 2571283.