MedKoo Cat#: 414479 | Name: Norgesterone

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Norgesterone, also known as norvinodrel or vinylestrenolone and sold under the brand name Vestalin, is a progestin medication which was formerly used in birth control pills for women but is now no longer marketed. It was used in combination with the estrogen ethinylestradiol. It is taken by mouth.

Chemical Structure

Norgesterone
Norgesterone
CAS#13563-60-5

Theoretical Analysis

MedKoo Cat#: 414479

Name: Norgesterone

CAS#: 13563-60-5

Chemical Formula: C20H28O2

Exact Mass: 300.2089

Molecular Weight: 300.44

Elemental Analysis: C, 79.96; H, 9.39; O, 10.65

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Norgesterone; norvinodrel; vinylestrenolone; Vestalin; NSC72160; NSC-72160; NSC 72160
IUPAC/Chemical Name
17alpha-Vinyl-5(10)-estrene-17beta-ol-3-one
InChi Key
YPVUHOBTCWJYNQ-SLHNCBLASA-N
InChi Code
InChI=1S/C20H28O2/c1-3-20(22)11-9-18-17-6-4-13-12-14(21)5-7-15(13)16(17)8-10-19(18,20)2/h3,16-18,22H,1,4-12H2,2H3/t16-,17-,18+,19+,20+/m1/s1
SMILES Code
C[C@@]12[C@](O)(C=C)CC[C@@]1([H])[C@]3([H])CCC4=C(CCC(C4)=O)[C@@]3([H])CC2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 300.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Minkin SF. Reply to Dr. Edwin B. McDaniel. Exaggerated claims of depo-provera safety. Women Health. 1981 Spring-Summer;6(1-2):125-9. PMID: 6223451. 2: Nakashima M, Kawabe Y, Aoyagi T, Furuichi I, Maeda K, Naito S, Kawakami A, Eguchi K. A case of eosinophilic myositis associated with orbital myositis. Mod Rheumatol. 2002 Mar;12(1):80-3. doi: 10.3109/s101650200014. PMID: 24383838. 3: ROGNONI V, ROSSI R. SUL TRATTAMENTO DELLA DISMENORREA ESSENZIALE CON L'ASSOCIAZIONE VINILESTRENOLONEETINILESTRADIOLO [ON TREATMENT OF ESSENTIAL DYSMENORRHEA WITH VINYLESTRENOLONE-ETHINYLESTRADIOL COMBINATION]. Minerva Ginecol. 1964 Jan 15;16:24-7. Italian. PMID: 14124188. 4: LUPO C, POGGI G. EFFETTI DEL VINILESTRENOLONE SULLA DINAMICA UTERINA "IN VITRO" [EFFECTS OF VINYLESTRENOLONE ON UTERINE DYNAMICS IN VITRO]. Riv Biol. 1964;57:SUPPL L:79-89. Italian. PMID: 14161840. 5: D INCERTIBONINI L, PAGANI C. DIAGNOSTI PRECOCE DI GRAVIDANZA CON IL TEST AL VINILESTRENOLONE-ETILILESTRADIOLO [EARLY DIAGNOSIS OF PREGNANCY WITH THE VINYLESTRENOLONE-ETHINYLESTRADIOL]. Ann Ostet Ginecol. 1964 Feb;86:103-28. Italian. PMID: 14156044. 6: D'INCERTI BONINI L, PAGANI C. [Clinical investigations of the progestational activity of vinylestrenolone]. Ann Ostet Ginecol. 1962 Apr;84:279-85. Italian. PMID: 13883015. 7: MALAGOLI F, SIDERI L. I FENOMENI EMOCOAGULATORI IN CORSO DI TRATTAMENTO CON L'ASSOCIAZIONE VINILESTRENOLONE-ETINILESTRADIOLO [BLOOD COAGULATION PHENOMENA IN THE COURSE OF TREATMENT WITH COMBINED VINYLESTRENOLONE AND ETHINYLESTRADIOL]. Gazz Med Ital. 1964 Apr;123:116-8. Italian. PMID: 14145737.