MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 577042 | Name: ML-1035 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ML 1035 is a benzamide that elicits contractions from guinea-pig non-stimulated ileum.

Chemical Structure

ML-1035 HCl
ML-1035 HCl
CAS#125557-35-9 (HCl)

Theoretical Analysis

MedKoo Cat#: 577042

Name: ML-1035 HCl

CAS#: 125557-35-9 (HCl)

Chemical Formula: C16H27Cl2N3O3S

Exact Mass: 411.1150

Molecular Weight: 412.37

Elemental Analysis: C, 46.60; H, 6.60; Cl, 17.19; N, 10.19; O, 11.64; S, 7.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
125557-35-9 (HCl) 54504-71-1 (free base)
Synonym
ML-1035 hydrochloride; ML-1035 HCl; ML 1035 HCl; ML1035 HCl; MDL 201035; MDL201035; MDL-201035
IUPAC/Chemical Name
Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-(2-(methylsulfinyl)ethoxy)-, hydrochloride (1:1)
InChi Key
KDAXHUZRHLYZML-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H26ClN3O3S.ClH/c1-4-20(5-2)7-6-19-16(21)12-10-13(17)14(18)11-15(12)23-8-9-24(3)22;/h10-11H,4-9,18H2,1-3H3,(H,19,21);1H
SMILES Code
Cl.CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OCC[S+](C)[O-]
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 412.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Rao N, Otis KW, Hwang KK. Sex-differences in the disposition of substituted benzamides: pharmacokinetics of a gastroprokinetic agent (4-amino-5-chloro-2-[2- (methylsulfinyl) ethoxy]-N-[2-(diethylamino)ethyl] benzamide hydrochloride) (ML-1035) in male and female New Zealand white rabbits. Biopharm Drug Dispos. 1992 Dec;13(9):681-91. doi: 10.1002/bdd.2510130906. PMID: 1467455. 2. Linnik MD, Butler BT, Elsea SH, Ahmed NK. Analysis of neurogenic contractions induced by ML-1035 and other benzamides in the guinea-pig non-stimulated isolated ileum. J Pharm Pharmacol. 1994 Jun;46(6):491-6. doi: 10.1111/j.2042-7158.1994.tb03833.x. PMID: 7932045. 3. Linnik MD, Butler BT, Gaddis RR, Ahmed NK. Analysis of serotonergic mechanisms underlying benzamide-induced gastroprokinesis. J Pharmacol Exp Ther. 1991 Nov;259(2):501-7. PMID: 1941605.